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Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator

Easily calculate and compute goldman-hodgkin-katz (ghk) membrane potential calculator with accurate equations, live formulas, and expert guidance.

Calculated Result
-68 mV

Resting Membrane Potential (V_m)

Resting Membrane Potential (V_m)

-68 mV

Nernst Potassium Potential M V

-91.8

Nernst Sodium Potential M V

66

Depolarization Risk Alert

NORMAL PHYSIOLOGICAL RESTING EXCITABILITY

-68 — mV

Calculation Breakdown

  1. Applied FormulaCalculates cellular resting membrane electrical potential Vm using the Goldman-Hodgkin-Katz (GHK) voltage equation based on intracellular and extracellular Na+, K+, and Cl- concentrations and relative permeabilities.V_m = \frac{RT}{F} \ln\left( \frac{P_{\text{K}} [\text{K}^+]_o + P_{\text{Na}} [\text{Na}^+]_o + P_{\text{Cl}} [\text{Cl}^-]_i}{P_{\text{K}} [\text{K}^+]_i + P_{\text{Na}} [\text{Na}^+]_i + P_{\text{Cl}} [\text{Cl}^-]_o} \right)

GHK Membrane Potential Metric Output

Interactive visualization based on your current inputs

Calculated Value
-68.0-50.8-33.5-16.31.0Resting Membrane Potential (V_m)

What Is the Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator?

This tool computes goldman-hodgkin-katz (ghk) membrane potential calculator with high precision arithmetic.

How Does the Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator Work?

Calculates cellular resting membrane electrical potential Vm using the Goldman-Hodgkin-Katz (GHK) voltage equation based on intracellular and extracellular Na+, K+, and Cl- concentrations and relative permeabilities.

Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator Formula & Variables

The core mathematical equation utilized by this calculator is expressed as:

Vm=RTFln⁡(PK[K+]o+PNa[Na+]o+PCl[Cl−]iPK[K+]i+PNa[Na+]i+PCl[Cl−]o)V_m = \frac{RT}{F} \ln\left( \frac{P_{\text{K}} [\text{K}^+]_o + P_{\text{Na}} [\text{Na}^+]_o + P_{\text{Cl}} [\text{Cl}^-]_i}{P_{\text{K}} [\text{K}^+]_i + P_{\text{Na}} [\text{Na}^+]_i + P_{\text{Cl}} [\text{Cl}^-]_o} \right)

Calculates cellular resting membrane electrical potential Vm using the Goldman-Hodgkin-Katz (GHK) voltage equation based on intracellular and extracellular Na+, K+, and Cl- concentrations and relative permeabilities.

How to Use the Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator

  1. Enter your parameters into the designated input fields to calculate the result immediately.

Step-by-Step Example Calculation

Goldman-Hodgkin-Katz (GHK) Membrane Potential Calculator Example

Input Values:

extracellularPotassiumMmolPerL:4.5
intracellularPotassiumMmolPerL:140
extracellularSodiumMmolPerL:142
relativeSodiumPermeabilityPNaOverPK:0.04
Worked Steps: Sample evaluation based on standard reference conditions.

Understanding Your Result

The calculated primary figure indicates the optimal or required mV.

Factors That Affect the Result

  • Measurement tolerances, operational variance, and real-world conditions.

When Should You Use This Calculator?

  • Everyday budgeting, technical homework, professional estimation, and household projects.

Assumptions & Limitations

  • Assumes standard atmospheric or environmental parameters unless specified.

Frequently Asked Questions

Calculation Accuracy & Reference Note

Double-precision IEEE 754 arithmetic with validated empirical constants.

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